Mayelana

I-T&T Scientific

Ikusasa Lezidakamizwa

I-T&T Scientific iyinkampani yezinsizakalo zemithi ehlanganisa konke kanye ne-biotechnology. Inkundla yokukhiqiza ye-T&T ekalayo, yekhwalithi ephezulu, neshibhile ikhiqiza imithi yokugoma enembile, esezingeni eliphezulu, kanye nelawulwa ngekhwalithi. Izinsizakalo zihlanganisa ukwakhiwa, ukuthuthukisa, kanye nokukhiqizwa kwe-cGMP kusukela ezigabeni zangaphambi komtholampilo kuye kwezentengiso zemikhiqizo yezidakamizwa esekelwe ku-nanoparticle enama-API ahlukahlukene asukela kuma-microliter kuya kumaqoqwana angaphezu kwamalitha ayi-100. I-T&T inamakhasimende kanye nobudlelwano emazweni angaphezu kuka-50, ngesiko lokuthuthukisa amakhono eligxile kumakhasimende futhi eliyingqayizivele ukudala ngempumelelo inkundla yemithi yomuntu siqu nehumushayo ezayo.

I-T&T Scientific iyinkampani eyaziwa emhlabeni wonke ye-Biopharmaceutical and Medical Devices Technologies, Services, and Manufacturing Company. I-T&T iyikhaya lokwenziwa kwe-lipid nanoparticle okuthuthuke kakhulu emhlabeni wonke kanye nobuchwepheshe bokukhiqiza kuzo zonke izikali zocwaningo, ukuthuthukiswa, kanye nokukhiqizwa kwe-cGMP. Sihlinzeka ngezinsizakalo zemithi nezinsiza zezokwelapha (ikakhulukazi ngobuchwepheshe bethu) kanye nobuchwepheshe bokulungiselela nokwenza ama-liposomes kanye ne-lipid nanoparticles inoveli yama-nanomedicines. Ngaphezu kwalokho, sinikezela ngezinsiza eziningi zenkontileka ye-GMP nezingezona eze-GMP zocwaningo nokuthuthukiswa kokwakhiwa, indlela yokuhlaziya nokuthuthukiswa kwenqubo yokukhiqiza, kanye nokusekela imisebenzi yokufaneleka nokuqinisekisa endaweni yethu esezingeni eliphezulu engu-15,000 sq. ft. izindawo ezihlanzekile.

Umgomo wethu ukuhlinzeka ngohlu olubanzi lwemikhiqizo namasevisi asezingeni eliphezulu futhi ahlelekile ngokuletha ngokushesha ukuze kusekelwe ucwaningo lwakho, ukuthuthukiswa, kanye nezidingo zokukhiqiza. Ithimba kwa-T&T Scientific linobuchwepheshe nolwazi oluningi ku-lipid nanoparticle kanye nokwakhiwa kwe-liposome ekufakweni kwezicelo zokulethwa kwezidakamizwa. Sihlonyiswe kahle ngamakhono okusebenza kanye nethimba Lokuqinisekisa Ikhwalithi elidingekayo ukuze kwenziwe iqoqo lemitholampilo nelezentengiselwano lamakhambi asetshenziswa ekwelapheni nasekugomeni. I-T&T ibhaliswe ne-US Food and Drug Administration (US FDA - T&T Scientific FDA Registration FEI Number 3015266446) futhi okwamanje yenza izixazululo ze-lipid-based nanomedicine ukuze zisetshenziswe ezivivinyweni zomtholampilo zabantu.

Ubuchwepheshe bethu buhlanganisa i-NanoSizer MINI, I-AUTO, ne-FLOW. Lawa mapulatifomu amelela ubuchwepheshe bamuva bomjovo we-extrusion kanye ne-ethanol eqondile yokukhiqiza okulula, konke-in-one, okuhlanjululwayo kwama-liposomes nama-lipid nanoparticles anezinzuzo ezimbalwa zokuncintisana ezihlanganisa ikhwalithi, intengo, kanye nokusebenziseka kalula. I-T&T's nethimba elaziwayo lokuqamba lososayensi abasebenza ku-lipid, i-polymer, kanye nobuchwepheshe bokwakhiwa kwe-nanoparticle eyingxube, i-ProFECT, yokwelashwa nokulethwa kwezakhi zofuzo eziphephile nezisebenzayo. Lawa masistimu okwakhiwa aklanyelwe ukuvikela ama-nucleic acid afana nama-RNA nama-DNA ekonakalisweni ukuze asetshenziswe ekugomeni nasezinhlelweni zokwelapha. Vakashela iwebhusayithi yethu noma uthinte uchwepheshe we-T&T ukuze ufunde kabanzi mayelana nohlu olugcwele lwe-T&T lwe-lipids, ama-liposomes angokwezifiso, nemikhiqizo ye-lipid nanoparticle, ubuchwepheshe, kanye nezinsizakalo.Phakathi neminyaka eyisikhombisa edlule ngosizo lweqembu elimangalisayo, i-T&T yenze okubalulekile. ingqophamlando yokuletha ibhizinisi elivela emhlabeni wonke e-Knoxville, manje esesiqalisiwe futhi esilungiselelwe ukukalwa okukhulu kwengqalasizinda ebanzi neqinile eyakhiwe.

Imisebenzi

UKUTHUTHUKISWA KWE-PRECLINICAL NOKUTHUTHUKISWA KOKWAKHA
  • Ukuthuthukiswa Kokwakhiwa Kwangaphambi Komtholampilo, Nokuthuthukisa
  • Ukudlulisa Ubuchwepheshe Nokuthuthukiswa Kwemithi: Izinqubo Zokukhiqiza kanye Nokuthuthukiswa Kwezindlela Zokuhlaziya
  • Ukwenziwa Kweqoqo Lomtholampilo, kanye Nokukhishwa KweLothi 
  • Ukulungiselela I-CDMO Yezemithi Zonke Izidingo Zokukhiqiza Zokuthunyelwa kwe-IND
  • Izinhlelo Zezifundo Zokuzinza Zemikhiqizo Yemithi Yemithi Ezigabeni Zomtholampilo
  • I-cGMP Material Storage Amandla Athobela Ngokunembile Imihlahlandlela Yokulawulwa Kokudla Nezidakamizwa
  • Ukuhlelwa Kokukhiqiza Kwemitholampilo Nezohwebo kanye Nokwenziwa Kokukhiqiza Okuthobela Ngokugcwele, Gcwalisa, futhi Uqede, kanye Nokukhishwa Kwenqwaba Yemikhiqizo Yezidakamizwa Nemikhiqizo Yezidakamizwa 

Imikhiqizo

  • I-NanoSizer FLOW yokulinganisa nokwakha ama-Nanoparticle Drug Delivery Systems kanye ne-Encapsulating API's Solvent Injection Technology Ikhiqiza Ikhwalithi Ephakeme Kakhulu Ye-Nanomedicines Nge-High Throughp ut, Izindleko Eziphansi, I-GMP Egcwele, kanye Ne-Counter Top.
  • I-NanoSizer Extruder Yokwenza Nokulinganisa I-Liposomes kanye ne-Lipid/Polymer Nanoparticles: I-Handheld, I-Liposomes Ezenzakalelayo Ngokugcwele, kanye Ne-Lipid Nanoparticle Extruders Itholakala Ezinguqulweni Eziyinyumba: Esheshayo, Elula, Ikhwalithi Ephezulu Nezindleko Eziphansi
  • Ilungele Ukusebenzisa Ama-Nanoparticle Reagents, Amamiksi, i-Multilamellar kanye ne-Unilamellar Vesicles, Zonke Izixazululo, Ama-Buffers, kanye Nezincibilikisi Ezihlanganisiwe Zilungele Ukuhlolwa Kwakho
  • Amasistimu Okulethwa Kwezidakamizwa Ngokwezifiso: Idizayini Yesistimu Yokulethwa Kwezidakamizwa Ngokwezifiso, Amasampuli, Izimpawu Zangaphambi Komtholampilo Nezimpawu Zomtholampilo Nokuthuthukiswa

Mayelana

I-T&T Scientific

Ikusasa Lezidakamizwa

I-T&T Scientific iyinkampani yezinsizakalo zemithi ehlanganisa konke kanye ne-biotechnology. Inkundla yokukhiqiza ye-T&T ekalayo, yekhwalithi ephezulu, neshibhile ikhiqiza imithi yokugoma enembile, esezingeni eliphezulu, kanye nelawulwa ngekhwalithi. Izinsizakalo zihlanganisa ukwakhiwa, ukuthuthukisa, kanye nokukhiqizwa kwe-cGMP kusukela ezigabeni zangaphambi komtholampilo kuye kwezentengiso zemikhiqizo yezidakamizwa esekelwe ku-nanoparticle enama-API ahlukahlukene asukela kuma-microliter kuya kumaqoqwana angaphezu kwamalitha ayi-100. I-T&T inamakhasimende kanye nobudlelwano emazweni angaphezu kuka-50, ngesiko lokuthuthukisa amakhono eligxile kumakhasimende futhi eliyingqayizivele ukudala ngempumelelo inkundla yemithi yomuntu siqu nehumushayo ezayo.

I-T&T Scientific iyinkampani eyaziwa emhlabeni wonke ye-Biopharmaceutical and Medical Devices Technologies, Services, and Manufacturing Company. I-T&T iyikhaya lokwenziwa kwe-lipid nanoparticle okuthuthuke kakhulu emhlabeni wonke kanye nobuchwepheshe bokukhiqiza kuzo zonke izikali zocwaningo, ukuthuthukiswa, kanye nokukhiqizwa kwe-cGMP. Sihlinzeka ngezinsizakalo zemithi nezinsiza zezokwelapha (ikakhulukazi ngobuchwepheshe bethu) kanye nobuchwepheshe bokulungiselela nokwenza ama-liposomes kanye ne-lipid nanoparticles inoveli yama-nanomedicines. Ngaphezu kwalokho, sinikezela ngezinsiza eziningi zenkontileka ye-GMP nezingezona eze-GMP zocwaningo nokuthuthukiswa kokwakhiwa, indlela yokuhlaziya nokuthuthukiswa kwenqubo yokukhiqiza, kanye nokusekela imisebenzi yokufaneleka nokuqinisekisa endaweni yethu esezingeni eliphezulu engu-15,000 sq. ft. izindawo ezihlanzekile.

Umgomo wethu ukuhlinzeka ngohlu olubanzi lwemikhiqizo namasevisi asezingeni eliphezulu futhi ahlelekile ngokuletha ngokushesha ukuze kusekelwe ucwaningo lwakho, ukuthuthukiswa, kanye nezidingo zokukhiqiza. Ithimba kwa-T&T Scientific linobuchwepheshe nolwazi oluningi ku-lipid nanoparticle kanye nokwakhiwa kwe-liposome ekufakweni kwezicelo zokulethwa kwezidakamizwa. Sihlonyiswe kahle ngamakhono okusebenza kanye nethimba Lokuqinisekisa Ikhwalithi elidingekayo ukuze kwenziwe iqoqo lemitholampilo nelezentengiselwano lamakhambi asetshenziswa ekwelapheni nasekugomeni. I-T&T ibhaliswe ne-US Food and Drug Administration (US FDA - T&T Scientific FDA Registration FEI Number 3015266446) futhi okwamanje yenza izixazululo ze-lipid-based nanomedicine ukuze zisetshenziswe ezivivinyweni zomtholampilo zabantu.

Ubuchwepheshe bethu buhlanganisa i-NanoSizer MINI, I-AUTO, ne-FLOW. Lawa mapulatifomu amelela ubuchwepheshe bamuva bomjovo we-extrusion kanye ne-ethanol eqondile yokukhiqiza okulula, konke-in-one, okuhlanjululwayo kwama-liposomes nama-lipid nanoparticles anezinzuzo ezimbalwa zokuncintisana ezihlanganisa ikhwalithi, intengo, kanye nokusebenziseka kalula. I-T&T's nethimba elaziwayo lokuqamba lososayensi abasebenza ku-lipid, i-polymer, kanye nobuchwepheshe bokwakhiwa kwe-nanoparticle eyingxube, i-ProFECT, yokwelashwa nokulethwa kwezakhi zofuzo eziphephile nezisebenzayo. Lawa masistimu okwakhiwa aklanyelwe ukuvikela ama-nucleic acid afana nama-RNA nama-DNA ekonakalisweni ukuze asetshenziswe ekugomeni nasezinhlelweni zokwelapha. Vakashela iwebhusayithi yethu noma uthinte uchwepheshe we-T&T ukuze ufunde kabanzi mayelana nohlu olugcwele lwe-T&T lwe-lipids, ama-liposomes angokwezifiso, nemikhiqizo ye-lipid nanoparticle, ubuchwepheshe, kanye nezinsizakalo.Phakathi neminyaka eyisikhombisa edlule ngosizo lweqembu elimangalisayo, i-T&T yenze okubalulekile. ingqophamlando yokuletha ibhizinisi elivela emhlabeni wonke e-Knoxville, manje esesiqalisiwe futhi esilungiselelwe ukukalwa okukhulu kwengqalasizinda ebanzi neqinile eyakhiwe.

Imisebenzi

  • Ukuthuthukiswa Kokwakhiwa Kwangaphambi Komtholampilo, Nokuthuthukisa
  • Ukudlulisa Ubuchwepheshe Nokuthuthukiswa Kwemithi: Izinqubo Zokukhiqiza kanye Nokuthuthukiswa Kwezindlela Zokuhlaziya
  • Ukwenziwa Kweqoqo Lomtholampilo, kanye Nokukhishwa KweLothi 
  • Ukulungiselela I-CDMO Yezemithi Zonke Izidingo Zokukhiqiza Zokuthunyelwa kwe-IND
  • Izinhlelo Zezifundo Zokuzinza Zemikhiqizo Yemithi Yemithi Ezigabeni Zomtholampilo
  • I-cGMP Material Storage Amandla Athobela Ngokunembile Imihlahlandlela Yokulawulwa Kokudla Nezidakamizwa
  • Ukuhlelwa Kokukhiqiza Kwemitholampilo Nezohwebo kanye Nokwenziwa Kokukhiqiza Okuthobela Ngokugcwele, Gcwalisa, futhi Uqede, kanye Nokukhishwa Kwenqwaba Yemikhiqizo Yezidakamizwa Nemikhiqizo Yezidakamizwa 
UKUTHUTHUKISWA KWE-PRECLINICAL NOKUTHUTHUKISWA KOKWAKHA

Imikhiqizo

  • I-NanoSizer FLOW yokulinganisa nokwakha ama-Nanoparticle Drug Delivery Systems kanye ne-Encapsulating API's Solvent Injection Technology Ikhiqiza Ikhwalithi Ephakeme Kakhulu Ye-Nanomedicines Nge-High Throughp ut, Izindleko Eziphansi, I-GMP Egcwele, kanye Ne-Counter Top.
  • I-NanoSizer Extruder Yokwenza Nokulinganisa I-Liposomes kanye ne-Lipid/Polymer Nanoparticles: I-Handheld, I-Liposomes Ezenzakalelayo Ngokugcwele, kanye Ne-Lipid Nanoparticle Extruders Itholakala Ezinguqulweni Eziyinyumba: Esheshayo, Elula, Ikhwalithi Ephezulu Nezindleko Eziphansi
  • Ilungele Ukusebenzisa Ama-Nanoparticle Reagents, Amamiksi, i-Multilamellar kanye ne-Unilamellar Vesicles, Zonke Izixazululo, Ama-Buffers, kanye Nezincibilikisi Ezihlanganisiwe Zilungele Ukuhlolwa Kwakho
  • Amasistimu Okulethwa Kwezidakamizwa Ngokwezifiso: Idizayini Yesistimu Yokulethwa Kwezidakamizwa Ngokwezifiso, Amasampuli, Izimpawu Zangaphambi Komtholampilo Nezimpawu Zomtholampilo Nokuthuthukiswa