Okuhamba phambili Emhlabeni
Nanoparticles Drug Products
Manufacturing Platform:
I-NanoSizer FLOWTM

Thola Umkhawulo: Izinzuzo Zokuncintisana

  • Akukho Ukuzibophezela Nentengo Ephansi: Ngenkathi Ihlinzeka Ngamanani Ancintisana Kakhulu Wezinto Ezisetshenziswayo Nezinto Ezisetshenziswayo, i-T&T Scientific Ayidingi Ikhasimende Layo Ukuze Zizibophezele Isikhathi Eside Sesivumelwano Selayisensi noma Izinkokhelo Zemali. 
  • Ucwaningo Lokwengeza Ukukhiqiza Konke Kokukodwa: ukusuka ku-20mL ukuya ku-100s Liters, i-T&T Scientific NanoSizer FLOW Software, kanye ne-Hardware Platform Ivumela Abasebenzisi Ukwenza Ucwaningo Olukhulu Ngokweqiniso Lokusungula Nokwenza Imikhiqizo yabo Besebenzisa Inkundla Eyodwa.
  • Ukusebenza Okuphezulu: I-NanoSizer FLOW Technology GMP Ready System Ivumela Ukukhiqiza Okufika Ku-5-10L Amaminithi
  • hle: Ukulawulwa Okunembile Kosayizi, ne-Consistent Polydispersity Index (PDI) engaphansi kuka-0.08
  • Uhlelo lokusebenza olulawulwa ngokugcwele nolwenziwa ngendlela oyifisayo kanye neSofthiwe: I-Software kanye Nenkundla Yohlelo Lokusebenza Ivumela Umsebenzisi Ukwenza Ngokwezifiso Inqubo Ngokugcwele Nokulawula Amapharamitha Okukhiqiza 

Uhlolojikelele

I-T&T Scientific inikezela ngenkundla yokukhiqiza ye-nanomedicine ehamba phambili emhlabeni enezinga eliphansi, eliphansi, inani eliphezulu, ikhwalithi ephezulu, kanye nenhlobonhlobo yokusebenza. Uhlelo lwe-GMP lungasebenza futhi lucubungule u-50mL kuya okungenani ku-500L+ (Ahloliwe) ama-nanomedicine wokukhiqiza i-cGMP yokwelapha ngofuzo kanye nemithi yokugoma (okungukuthi, imithi yokwelapha ye-RNA kanye ne-COVID-19). I-NanoSizerTM technology has been developed over the years with great characterization and optimization procedures to achieve the precise and narrow size distribution of particles and producing highly encapsulated lipid nanoparticle APIs. We have reached the PDI as low as 0.05 and consistent encapsulation efficiency of over 99% after optimizing flow conditions for a given formulation. Moreover, the cell studies indicated a promising transfection and association of lipid nanoparticle mRNA into cells. T&T Scientific does not require any licensing and royalty fees or contracts for its clients. T&T Scientific culture believes clients should have no limitation when developing lifesaving novel pharmaceutical nanomedicine therapeutics and x Made Low Cost, High Quality, Small Volume to High Throughput (50mL-500L+) All in One GMP System & Never Pay for Licensing or Royalty to Produce Life Saving Therapeutics and Vaccines.

Imodeli YemikhiqizoblinkIsiteshiGMP
Inombolo Yemodeli YomkhiqizoI-TTE-024I-TTE-025I-TTE-023
Ideal Batch size0.5-50mL1-400mL20mL-100L+
Ukufakwa, Ukuqeqeshwa, Iwaranti
Ukufaneleka: IQ/OQ/PQ/PM (Ongakukhetha)
I-Inline Dilution kanye nokwenza ngokwezifiso
Ukulawula izinga lokushisa (Ongakukhetha)
Izinketho ze-PAT On-line Analytics
I-Inline Post Processing.Ukuhambisana kwe-TFF
Ukukhiqiza Okuqhubekayo
Isivumelwano Selayisensi
Izinkokhelo zeRoyalty
Inani$ 35,000.  UphenyoUphenyo

Inembile futhi Iyavumelana

Idatha Ibonisa ukuthi Imikhiqizo Yezidakamizwa Ye-Lipid Nanoparticle Ikhiqizwa Ngokunembile Futhi Ngokuvumelana Nezinhlobo Ezihlukene Zezinto Ezisizayo, I-Lipids kanye Ne-Polymers; kusuka kokuncane kuya kokusebenza okuphezulu.

I-Scalable futhi Ilawulwa Ngokunembile

I-T&T NanoSizer FLOW System Bonisa Ukucaciswa Okulawuleka Ngempela Kwemikhiqizo Yezidakamizwa Ye-Nanoparticles Ezimweni Ezihlukahlukene Zokugeleza Nezikali, Ezifana Nosayizi, kanye Nokusebenza Kwe-Ecapsulation.

Ukukhiqizwa Kweqoqwana Okungaguquguquki Nokuphindaphindwayo kuma-Long Runs

Ukuhlolwa Okuhlukahlukene Nemiphumela evela ku-T&T NanoSizer FLOW Inemibukiso Yokwenziwa Kwemikhiqizo Yezidakamizwa Ye-Nanoparticles Ukuze Ingaguquguquki Futhi Iphindaphindeke Usuku Nosuku Ngezinsuku Ezinde Nezikhathi Zokukhiqiza.

Buka

Nawa amavidiyo amathathu asheshayo anokubuka konke okusheshayo neziyalezo ze-NanoSizer FLOW GMP.

Isingeniso Esisheshayo

Lokhu ukuboniswa okusheshayo kanye nokubuka konke kwe-NanoSizer FLOW GMP 

Imashi

Here is a detailed demonstration of NanoSizer FLOW GMP.

Ukufundisa

Pre-installation training of NanoSizer FLOW 

Cela Ulwazi Olwengeziwe kanye Nokuboniswa Kwendawo/Okungeyona Isayithi